Search results for "Seed crystal"

showing 6 items of 6 documents

Modelling phase transition kinetics of chenodeoxycholic acid with the Runge–Kutta method

2009

Abstract The phase transition kinetics of two chenodeoxycholic acid polymorphic modifications— form I (stable at high temperature), form III (stable at low temperature) and the amorphous phase has been examined under various conditions of temperature and relative humidity. Form III conversion to form I was examined at high temperature conditions and was found to be non-spontaneous, requiring seed crystals for initiation. The formation kinetic model of form I was created incorporating the three-dimensional seed crystal growth, the phase transition rate proportion to the surface area of form I crystals, and the influence of the amorphous phase surface area changes with an empirical stage poin…

Phase transitionDifferential Thermal AnalysisSpectrophotometry InfraredDifferential equationClinical BiochemistryPharmaceutical ScienceThermodynamicsChenodeoxycholic AcidKinetic energyPhase TransitionAnalytical ChemistryReaction rate constantDrug StabilityX-Ray DiffractionDrug DiscoverySample preparationSpectroscopySeed crystalModels StatisticalCalorimetry Differential ScanningChemistryTemperatureKineticsRunge–Kutta methodsCrystallographyX-ray crystallographyCrystallizationJournal of Pharmaceutical and Biomedical Analysis
researchProduct

Application of enthalpy model for floating zone silicon crystal growth

2017

Abstract A 2D simplified crystal growth model based on the enthalpy method and coupled with a low-frequency harmonic electromagnetic model is developed to simulate the silicon crystal growth near the external triple point (ETP) and crystal melting on the open melting front of a polycrystalline feed rod in FZ crystal growth systems. Simulations of the crystal growth near the ETP show significant influence of the inhomogeneities of the EM power distribution on the crystal growth rate for a 4 in floating zone (FZ) system. The generated growth rate fluctuations are shown to be larger in the system with higher crystal pull rate. Simulations of crystal melting on the open melting front of the pol…

010302 applied physicsMaterials scienceTriple pointPhysics::OpticsCrystal growth02 engineering and technology021001 nanoscience & nanotechnologyCondensed Matter Physics01 natural sciencesMolecular physicsInorganic ChemistryCrystalMonocrystalline siliconCrystallographyCondensed Matter::Superconductivity0103 physical sciencesMaterials ChemistryLaser-heated pedestal growthCrystalliteGrowth rate0210 nano-technologySeed crystalJournal of Crystal Growth
researchProduct

Dry synthesis of B-MFI, MTN- and MTW-type materials

1997

Abstract B-MFI and MTN-type materials were synthesized via the fluoride route from dry powders in the complete absence of a solution phase. Amorphous precursors obtained by drying SiO 2 · Al 2 O 3 gels at 700°C were transformed into MTN-type material in the presence of dried NH 4 F and TMACl. Amorphous precursors obtained by drying SiO 2 gels at 700°C were transformed into B-MFI in the presence of dried NH 4 F, B 2 O 3 and TPABr. Water is formed as a reaction product. However, the water vapor pressure is appreciably below the water vapor saturation pressure under the given reaction conditions. In addition, syntheses using seed crystals were carried out successfully.

Reaction conditionsMaterials scienceChromatographyVapor pressureVapour pressure of waterGeneral EngineeringGeneral ChemistrySolution phaseAmorphous solidchemistry.chemical_compoundchemistryChemical engineeringGeneral Materials ScienceFluorideWater vaporSeed crystalMicroporous Materials
researchProduct

Influence of synthesis conditions on the morphology of Dodecasil 1H

1993

Abstract The synthesis of Dodecasil 1H was studied in the system SiO2/1-adamantylamin/NH3/water with the objective of controlling the particle size and the morphology of the crystals. Since nucleation occurs in a very early stage of the synthesis, the heating rate to the final temperature and/or holding points during heat up have a strong influence on both parameters. Crystals smaller than 150 μm could only be obtained by the use of seed crystals, which are completely consumed in the synthesis with subsequent new nucleation. Using seed crystals, the expensive template 1-adamantylamine can be substituted with cheaper reagents such as sodium dodecyl sulfate or trimethylethylammonium bromide a…

chemistry.chemical_compoundMorphology (linguistics)chemistryChemical engineeringBromideStereochemistryReagentNucleationfood and beveragesParticle sizeSodium dodecyl sulfateSeed crystalGeneral Environmental ScienceZeolites
researchProduct

Synthesis And Sorptive Properties Of Dodecasil 1 H With An Acessible Pore System

1994

Abstract The synthesis of Dodecasil 1H was studied in the system SiO2/1-adamantylamine/NH3/water with the objective of controlling the particle size and the morphology of the crystals. Since nucleation occurs in a very early stage of the synthesis, the heating rate to the final temperature have a strong influence on both parameters. Using seed crystals and such a heating programme, the expensive template 1-adamantylamine can be reduced to so small amounts, that a nearly template free pore system is achieved. The emptiness of the pore system was demonstrated from adsorption measurement using He and H2.

CrystallographyTemplate freeAdsorptionMorphology (linguistics)Materials scienceChemical engineeringNucleationPore systemParticle sizeSeed crystal
researchProduct

Determination of trace amounts of β tegafur in commercial α tegafur by powder X-ray diffractometric analysis.

2011

Abstract Objectives The main objective of this work was to develop a suitable analytical technique for determining trace amounts of the thermodynamically stable solid form in bulk samples of metastable form, to a sensitivity of 0.005%–1.0%. Tegafur (5-fluoro-1-(tetrahydro-2-furyl)-uracil) α and β crystalline forms were used as a model for this problem. Methods The trace content of the thermodynamically stable β polymorphic form in tegafur samples was increased by promoting phase transition from the bulk of thermodynamically metastable α form to β form, and achieving sufficient β form content for a quantitative powder X-ray diffractometry (PXRD) analysis. The phase transition was stimulated …

PharmacologyPhase transitionMaterials scienceTrace AmountsAnalytical chemistryPharmaceutical ScienceCrystallography X-RaySolventCrystallographyX-Ray DiffractionPhase (matter)ThermodynamicsSample preparationLeast-Squares AnalysisPowdersCrystallizationMass fractionSeed crystalPowder diffractionTegafurThe Journal of pharmacy and pharmacology
researchProduct